Abstract

Preliminary results from this study show that x-ray microcomputed tomography can be used to image model proteins for bone inducing growth factors. Small quantities (<1 μg protein/mg gelatin) of soybean trypsin inhibitor labeled with either gold nanoparticles or nonradioactive iodine were detected using synchrotron radiation. These results could lead to a new method of measuring the release profile of therapeutic proteins.

Original languageEnglish (US)
Pages (from-to)295-306
Number of pages12
JournalMacromolecular Symposia
Volume227
DOIs
StatePublished - Jul 2005

Keywords

  • Confocal microscopy
  • Drug delivery systems
  • Protein
  • Tomography
  • X-ray imaging

ASJC Scopus subject areas

  • Polymers and Plastics
  • Materials Chemistry

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