Abstract
The use of matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) in imaging neuropeptide distribution in exocrine tissues, ganglion sections, and from neuron subsections was discussed. The technology was used to characterize the distribution of known and novel peptides involved with the feeding and reproductive behaviors of Aplysia. MS imaging analysis provided more accurate spatial information on the chemical messengers contained in both intracellular and extracellular regions of cultured cells and networks. The method was found to be useful to probe neuropeptide processing, release, and transport to increase understanding of the diversity and interaction of signal mediators in simple neuronal networks.
Original language | English (US) |
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Title of host publication | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics |
Pages | 777-778 |
Number of pages | 2 |
State | Published - 2002 |
Event | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States Duration: Jun 2 2002 → Jun 6 2002 |
Other
Other | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics |
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Country/Territory | United States |
City | Orlando, FL |
Period | 6/2/02 → 6/6/02 |
ASJC Scopus subject areas
- Spectroscopy