Abstract

Plasmon-resonant gold nanorods (GNRs) can serve as imaging agents for spectroscopic optical coherence tomography (SOCT). The aspect ratio of the GNRs is adjusted for maximum absorption in the far red to create a partial spectral overlap with the short-wavelength edge of the near-infrared SOCT imaging band. The spectroscopic absorption profile of the GNRs is incorporated into a depth-resolved algorithm for mapping the relative GNR density within OCT images. This technique enables us to image GNR distributions in excised human breast carcinomas, demonstrating their potential as OCT contrast agents in heterogeneous, highly scattering tissues.

Original languageEnglish (US)
Pages (from-to)6407-6411
Number of pages5
JournalJournal of Materials Chemistry
Volume19
Issue number35
DOIs
StatePublished - 2009

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Chemistry

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