TY - GEN
T1 - Image reconstruction in photoacoustic tomography with heterogeneous media using an iterative method
AU - Huang, Chao
AU - Wang, Kun
AU - Wang, Lihong V.
AU - Anastasio, Mark A.
PY - 2013
Y1 - 2013
N2 - There remains an urgent need to develop effective photoacoustic computed tomography (PACT) image recon- struction methods for use with acoustically inhomogeneous media. Transcranial PACT brain imaging is an im- portant example of an emerging imaging application that would benefit greatly from this. Existing approaches to PACT image reconstruction in acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or make impractical assumptions regarding the measurement geometry. In this work, we develop and investigate a full-wave approach to iterative image reconstruction in PACT for media possessing inhomogeneous speed-of-sound and mass density distributions. A key contribution of the work is the formulation of a procedure to implement a matched discrete forward and backprojection operator pair, which facilitates the application of a wide range of modern iterative image reconstruction algorithms. This presents the opportunity to employ application-specific regularization methods to mitigate image artifacts due to mea- surement data incompleteness and noise. Our results establish that the proposed image reconstruction method can effectively compensate for acoustic aberration and reduces artifacts in the reconstructed image.
AB - There remains an urgent need to develop effective photoacoustic computed tomography (PACT) image recon- struction methods for use with acoustically inhomogeneous media. Transcranial PACT brain imaging is an im- portant example of an emerging imaging application that would benefit greatly from this. Existing approaches to PACT image reconstruction in acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or make impractical assumptions regarding the measurement geometry. In this work, we develop and investigate a full-wave approach to iterative image reconstruction in PACT for media possessing inhomogeneous speed-of-sound and mass density distributions. A key contribution of the work is the formulation of a procedure to implement a matched discrete forward and backprojection operator pair, which facilitates the application of a wide range of modern iterative image reconstruction algorithms. This presents the opportunity to employ application-specific regularization methods to mitigate image artifacts due to mea- surement data incompleteness and noise. Our results establish that the proposed image reconstruction method can effectively compensate for acoustic aberration and reduces artifacts in the reconstructed image.
KW - Photoacoustic tomography
KW - acoustic heterogeneity
KW - iterative image reconstruction
KW - k-space pseudospectral method
KW - optoacoustic tomography
KW - thermoacoustic tomography
UR - http://www.scopus.com/inward/record.url?scp=84878087321&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84878087321&partnerID=8YFLogxK
U2 - 10.1117/12.2007072
DO - 10.1117/12.2007072
M3 - Conference contribution
AN - SCOPUS:84878087321
SN - 9780819493507
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Photons Plus Ultrasound
T2 - Photons Plus Ultrasound: Imaging and Sensing 2013
Y2 - 3 February 2013 through 5 February 2013
ER -