Image reconstruction in photoacoustic tomography involving layered acoustic media

Robert W. Schoonover, Mark A. Anastasio

Research output: Contribution to journalArticlepeer-review


Photoacoustic tomography (PAT), also known as thermoacoustic or optoacoustic tomography, is a rapidly emerging biomedical imaging technique that combines optical image contrast with ultrasound detection principles. Most existing reconstruction algorithms for PAT assume the object of interest possesses homogeneous acoustic properties. The images produced by such algorithms can contain significant distortions and artifacts when the object's acoustic properties are spatially variant. In this work, we establish an image reconstruction formula for PAT applications in which a planar detection surface is employed and the to-be-imaged optical absorber is embedded in a known planar layered acoustic medium. The reconstruction formula is exact in a mathematical sense and accounts for multiple acoustic reflections between the layers of the medium. Computer-simulation studies are conducted to demonstrate and investigate the proposed method.

Original languageEnglish (US)
Pages (from-to)1114-1120
Number of pages7
JournalJournal of the Optical Society of America A: Optics and Image Science, and Vision
Issue number6
StatePublished - Jun 2011
Externally publishedYes

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Computer Vision and Pattern Recognition


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