TY - JOUR
T1 - Hydroxyurea inhibition of greening, macromolecule synthesis and cell division in Euglena gracilis
AU - Buetow, D. E.
AU - Mego, J. L.
PY - 1967/2/28
Y1 - 1967/2/28
N2 - Hydroxyurea inhibits chlorophyll synthesis and cell division in heat-bleached or dark-grown Euglena gracilis. 50 % inhibition of chlorophyll synthesis occurs at 0.02-0.035 M hydroxyurea. Euglena multiplies with a normal generation time and can at least partly recover the ability to green following removal of hydroxyurea. The syntheses of chlorophyll, DNA, RNA and protein are inhibited by hydroxyurea, that of chlorophyll being the most sensitive, followed in order by DNA, RNA and protein.
AB - Hydroxyurea inhibits chlorophyll synthesis and cell division in heat-bleached or dark-grown Euglena gracilis. 50 % inhibition of chlorophyll synthesis occurs at 0.02-0.035 M hydroxyurea. Euglena multiplies with a normal generation time and can at least partly recover the ability to green following removal of hydroxyurea. The syntheses of chlorophyll, DNA, RNA and protein are inhibited by hydroxyurea, that of chlorophyll being the most sensitive, followed in order by DNA, RNA and protein.
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U2 - 10.1016/0005-2787(67)90016-0
DO - 10.1016/0005-2787(67)90016-0
M3 - Article
AN - SCOPUS:49949141110
VL - 134
SP - 395
EP - 401
JO - BBA Section Nucleic Acids And Protein Synthesis
JF - BBA Section Nucleic Acids And Protein Synthesis
SN - 0005-2787
IS - 2
ER -