Hydrodynamic trap for single particles and cells

Melikhan Tanyeri; Eric M. Johnson-Chavarria; Charles M. Schroeder

doi:10.1063/1.3431664

Hydrodynamic trap for single particles and cells

Melikhan Tanyeri, Eric M. Johnson-Chavarria, Charles M. Schroeder

Research output: Contribution to journal › Article › peer-review

Abstract

Trapping and manipulation of microscale and nanoscale particles is demonstrated using the sole action of hydrodynamic forces. We developed an automated particle trap based on a stagnation point flow generated in a microfluidic device. The hydrodynamic trap enables confinement and manipulation of single particles in low viscosity (1-10 cP) aqueous solution. Using this method, we trapped microscale and nanoscale particles (100 nm-15 μm) for long time scales (minutes to hours). We demonstrate particle confinement to within 1 μm of the trap center, corresponding to a trap stiffness of ∼ 10 ^-5 - 10^-4 pN/nm.

Original language	English (US)
Article number	224101
Journal	Applied Physics Letters
Volume	96
Issue number	22
DOIs	https://doi.org/10.1063/1.3431664
State	Published - May 31 2010

ASJC Scopus subject areas

Physics and Astronomy (miscellaneous)

Online availability

10.1063/1.3431664

Library availability

Discover UIUC Full Text

Cite this

@article{b9726da1efc94c4e8d7822a1bea9bfc0,

title = "Hydrodynamic trap for single particles and cells",

abstract = "Trapping and manipulation of microscale and nanoscale particles is demonstrated using the sole action of hydrodynamic forces. We developed an automated particle trap based on a stagnation point flow generated in a microfluidic device. The hydrodynamic trap enables confinement and manipulation of single particles in low viscosity (1-10 cP) aqueous solution. Using this method, we trapped microscale and nanoscale particles (100 nm-15 μm) for long time scales (minutes to hours). We demonstrate particle confinement to within 1 μm of the trap center, corresponding to a trap stiffness of ∼ 10 -5 - 10-4 pN/nm.",

author = "Melikhan Tanyeri and Johnson-Chavarria, {Eric M.} and Schroeder, {Charles M.}",

note = "Funding Information: This work was funded by an NIH Pathway to Independence (PI) Award, under Grant No. 4R00HG004183-03. ",

year = "2010",

month = may,

day = "31",

doi = "10.1063/1.3431664",

language = "English (US)",

volume = "96",

journal = "Applied Physics Letters",

issn = "0003-6951",

publisher = "American Institute of Physics Publising LLC",

number = "22",

}

TY - JOUR

T1 - Hydrodynamic trap for single particles and cells

AU - Tanyeri, Melikhan

AU - Johnson-Chavarria, Eric M.

AU - Schroeder, Charles M.

N1 - Funding Information: This work was funded by an NIH Pathway to Independence (PI) Award, under Grant No. 4R00HG004183-03.

PY - 2010/5/31

Y1 - 2010/5/31

N2 - Trapping and manipulation of microscale and nanoscale particles is demonstrated using the sole action of hydrodynamic forces. We developed an automated particle trap based on a stagnation point flow generated in a microfluidic device. The hydrodynamic trap enables confinement and manipulation of single particles in low viscosity (1-10 cP) aqueous solution. Using this method, we trapped microscale and nanoscale particles (100 nm-15 μm) for long time scales (minutes to hours). We demonstrate particle confinement to within 1 μm of the trap center, corresponding to a trap stiffness of ∼ 10 -5 - 10-4 pN/nm.

AB - Trapping and manipulation of microscale and nanoscale particles is demonstrated using the sole action of hydrodynamic forces. We developed an automated particle trap based on a stagnation point flow generated in a microfluidic device. The hydrodynamic trap enables confinement and manipulation of single particles in low viscosity (1-10 cP) aqueous solution. Using this method, we trapped microscale and nanoscale particles (100 nm-15 μm) for long time scales (minutes to hours). We demonstrate particle confinement to within 1 μm of the trap center, corresponding to a trap stiffness of ∼ 10 -5 - 10-4 pN/nm.

UR - http://www.scopus.com/inward/record.url?scp=77953586223&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77953586223&partnerID=8YFLogxK

U2 - 10.1063/1.3431664

DO - 10.1063/1.3431664

M3 - Article

C2 - 20585593

AN - SCOPUS:77953586223

VL - 96

JO - Applied Physics Letters

JF - Applied Physics Letters

SN - 0003-6951

IS - 22

M1 - 224101

ER -

Hydrodynamic trap for single particles and cells

Abstract

ASJC Scopus subject areas

Online availability

Library availability

Related links

Fingerprint

Cite this