Hydrodynamic trap for single particles and cells

Melikhan Tanyeri, Eric M. Johnson-Chavarria, Charles M. Schroeder

Research output: Contribution to journalArticlepeer-review

Abstract

Trapping and manipulation of microscale and nanoscale particles is demonstrated using the sole action of hydrodynamic forces. We developed an automated particle trap based on a stagnation point flow generated in a microfluidic device. The hydrodynamic trap enables confinement and manipulation of single particles in low viscosity (1-10 cP) aqueous solution. Using this method, we trapped microscale and nanoscale particles (100 nm-15 μm) for long time scales (minutes to hours). We demonstrate particle confinement to within 1 μm of the trap center, corresponding to a trap stiffness of ∼ 10 -5 - 10-4 pN/nm.

Original languageEnglish (US)
Article number224101
JournalApplied Physics Letters
Volume96
Issue number22
DOIs
StatePublished - May 31 2010

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

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