Human TLRs 10 and 1 share common mechanisms of innate immune sensing but not signaling

Keyphrases

• Common Mechanisms 100%
• Toll-like Receptor 2 (TLR2) 100%
• Innate Immune Sensing 100%
• TLR10 100%
• TLR1 50%
• Microbes 25%
• Lipopeptide 25%
• TLR6 25%
• Adaptor 12%
• NF-B 12%
• Immune Response 12%
• Computational Modeling 12%
• Co-immunoprecipitation (co-IP) 12%
• Dimer Interface 12%
• Mutational Analysis 12%
• Fungi 12%
• Innate Immune Response 12%
• Interleukin-8 12%
• Signaling Domain 12%
• Intracellular Signaling 12%
• Family Members 12%
• Phylogenetic Analysis 12%
• Receptor Complex 12%
• Modeling Analysis 12%
• Host Inflammation 12%
• Phagosome 12%
• Signal Functions 12%
• Myeloid Differentiation Factor 88 (MyD88) 12%
• Adaptive Immune Response 12%
• Innate Immune Recognition 12%
• Activating Receptors 12%
• Chimeric Antigen Receptor T Cells (CAR-T) 12%
• Recognition Domain 12%

Immunology and Microbiology

• TLR 1 100%
• TLR10 100%
• TLR2 88%
• Agonist 33%
• Microorganism 22%
• TLR6 22%
• Immune Response 11%
• Phylogeny 11%
• Antigen Recognition 11%
• Innate Immune System 11%
• Phagosome 11%
• Intracellular Signaling 11%
• Adaptive Immune System 11%