TY - JOUR
T1 - House-dust mite allergen and asthma
AU - Harding, Clifford V.
AU - Kelso, John M.
AU - Rose, William B.
AU - Sporik, Richard B.
AU - Holgate, Stephen T.
AU - Platts-Mills, Thomas A.E.
AU - Cogswell, Jeremy J.
PY - 1991/1/31
Y1 - 1991/1/31
N2 - I believe that Sporik et al. (Aug. 23 issue)1 overstated the cause for a causal association between exposure to house-dust mite antigen and bronchial asthma. Rather, their data may be largely explained by the established relation between atopy and asthma. As the authors note, increased responsiveness to the mite antigen and bronchial asthma are both associated strongly with atopy (their Fig. 1). To investigate the relation between exposure to the antigen and subsequent asthma, the authors measure the concentration of the Der p (Dermatophagoides pteronyssinus) I antigen, as micrograms per gram of dust. Unfortunately, this does not …
AB - I believe that Sporik et al. (Aug. 23 issue)1 overstated the cause for a causal association between exposure to house-dust mite antigen and bronchial asthma. Rather, their data may be largely explained by the established relation between atopy and asthma. As the authors note, increased responsiveness to the mite antigen and bronchial asthma are both associated strongly with atopy (their Fig. 1). To investigate the relation between exposure to the antigen and subsequent asthma, the authors measure the concentration of the Der p (Dermatophagoides pteronyssinus) I antigen, as micrograms per gram of dust. Unfortunately, this does not …
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U2 - 10.1056/NEJM199101313240512
DO - 10.1056/NEJM199101313240512
M3 - Letter
C2 - 1986295
AN - SCOPUS:0026058389
SN - 0028-4793
VL - 324
SP - 337
EP - 338
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 5
ER -