House-dust mite allergen and asthma

Clifford V. Harding, John M. Kelso, William B. Rose, Richard B. Sporik, Stephen T. Holgate, Thomas A.E. Platts-Mills, Jeremy J. Cogswell

Research output: Contribution to journalLetterpeer-review


I believe that Sporik et al. (Aug. 23 issue)1 overstated the cause for a causal association between exposure to house-dust mite antigen and bronchial asthma. Rather, their data may be largely explained by the established relation between atopy and asthma. As the authors note, increased responsiveness to the mite antigen and bronchial asthma are both associated strongly with atopy (their Fig. 1). To investigate the relation between exposure to the antigen and subsequent asthma, the authors measure the concentration of the Der p (Dermatophagoides pteronyssinus) I antigen, as micrograms per gram of dust. Unfortunately, this does not …

Original languageEnglish (US)
Pages (from-to)337-338
Number of pages2
JournalNew England Journal of Medicine
Issue number5
StatePublished - Jan 31 1991

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'House-dust mite allergen and asthma'. Together they form a unique fingerprint.

Cite this