Highly non-linear contrast agent oscillations: The compression-only behavior

S. M. Van Der Meer; P. G. Marmottant; S. Hilgenfeldt; M. Versluis; D. Lohse; C. T. Chin; A. Bouakaz; F. Mastik; M. Emmer; N. De Jong

doi:10.1109/ULTSYM.2005.1603012

Highly non-linear contrast agent oscillations: The compression-only behavior

S. M. Van Der Meer, P. G. Marmottant, S. Hilgenfeldt, M. Versluis, D. Lohse, C. T. Chin, A. Bouakaz, F. Mastik, M. Emmer, N. De Jong

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Here we report the observation of a highly non-linear bubble response of phospholipid coated contrast agents, termed 'compression-only behavior' where the microbubbles only compress, yet hardly expand. The occurrence of this phenomenon has been studied retrospectively and it was found that 33% of the examined cases show this behavior. The compression-only behavior is described by a newly developed shell model for phospholipid coated bubbles. The model extends previous elastic models with shell compressibility, a buckling radius and a break-up tension. It also predicts large amplitude oscillations, and bubble break-up.

Original language	English (US)
Title of host publication	2005 IEEE Ultrasonics Symposium
Pages	974-976
Number of pages	3
DOIs	https://doi.org/10.1109/ULTSYM.2005.1603012
State	Published - 2005
Externally published	Yes
Event	2005 IEEE Ultrasonics Symposium - Rotterdam, Netherlands Duration: Sep 18 2005 → Sep 21 2005

Publication series

Name	Proceedings - IEEE Ultrasonics Symposium
Volume	2
ISSN (Print)	1051-0117

Other

Other	2005 IEEE Ultrasonics Symposium
Country/Territory	Netherlands
City	Rotterdam
Period	9/18/05 → 9/21/05

Keywords

Buckling model
Compression-only
Contrast agents

ASJC Scopus subject areas

Acoustics and Ultrasonics

Online availability

10.1109/ULTSYM.2005.1603012

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Van Der Meer, S. M., Marmottant, P. G., Hilgenfeldt, S., Versluis, M., Lohse, D., Chin, C. T., Bouakaz, A., Mastik, F., Emmer, M., & De Jong, N. (2005). Highly non-linear contrast agent oscillations: The compression-only behavior. In 2005 IEEE Ultrasonics Symposium (pp. 974-976). Article 1603012 (Proceedings - IEEE Ultrasonics Symposium; Vol. 2). https://doi.org/10.1109/ULTSYM.2005.1603012

Van Der Meer, SM, Marmottant, PG, Hilgenfeldt, S, Versluis, M, Lohse, D, Chin, CT, Bouakaz, A, Mastik, F, Emmer, M & De Jong, N 2005, Highly non-linear contrast agent oscillations: The compression-only behavior. in 2005 IEEE Ultrasonics Symposium., 1603012, Proceedings - IEEE Ultrasonics Symposium, vol. 2, pp. 974-976, 2005 IEEE Ultrasonics Symposium, Rotterdam, Netherlands, 9/18/05. https://doi.org/10.1109/ULTSYM.2005.1603012

@inproceedings{339e773b287f4aea9cce87e7f99d12c1,

title = "Highly non-linear contrast agent oscillations: The compression-only behavior",

abstract = "Here we report the observation of a highly non-linear bubble response of phospholipid coated contrast agents, termed 'compression-only behavior' where the microbubbles only compress, yet hardly expand. The occurrence of this phenomenon has been studied retrospectively and it was found that 33% of the examined cases show this behavior. The compression-only behavior is described by a newly developed shell model for phospholipid coated bubbles. The model extends previous elastic models with shell compressibility, a buckling radius and a break-up tension. It also predicts large amplitude oscillations, and bubble break-up.",

keywords = "Buckling model, Compression-only, Contrast agents",

author = "{Van Der Meer}, {S. M.} and Marmottant, {P. G.} and S. Hilgenfeldt and M. Versluis and D. Lohse and Chin, {C. T.} and A. Bouakaz and F. Mastik and M. Emmer and {De Jong}, N.",

year = "2005",

doi = "10.1109/ULTSYM.2005.1603012",

language = "English (US)",

isbn = "0780393821",

series = "Proceedings - IEEE Ultrasonics Symposium",

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AU - Van Der Meer, S. M.

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AU - Hilgenfeldt, S.

AU - Versluis, M.

AU - Lohse, D.

AU - Chin, C. T.

AU - Bouakaz, A.

AU - Mastik, F.

AU - Emmer, M.

AU - De Jong, N.

PY - 2005

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N2 - Here we report the observation of a highly non-linear bubble response of phospholipid coated contrast agents, termed 'compression-only behavior' where the microbubbles only compress, yet hardly expand. The occurrence of this phenomenon has been studied retrospectively and it was found that 33% of the examined cases show this behavior. The compression-only behavior is described by a newly developed shell model for phospholipid coated bubbles. The model extends previous elastic models with shell compressibility, a buckling radius and a break-up tension. It also predicts large amplitude oscillations, and bubble break-up.

AB - Here we report the observation of a highly non-linear bubble response of phospholipid coated contrast agents, termed 'compression-only behavior' where the microbubbles only compress, yet hardly expand. The occurrence of this phenomenon has been studied retrospectively and it was found that 33% of the examined cases show this behavior. The compression-only behavior is described by a newly developed shell model for phospholipid coated bubbles. The model extends previous elastic models with shell compressibility, a buckling radius and a break-up tension. It also predicts large amplitude oscillations, and bubble break-up.

KW - Buckling model

KW - Compression-only

KW - Contrast agents

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Highly non-linear contrast agent oscillations: The compression-only behavior

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Keywords

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