Abstract
We report the heterologous production of Ala(0)actagardine in E. coli by co-expression of the substrate peptide GarA and its modification enzymes GarM and GarO. The activity of GarO, a luciferase-like monooxygenase that introduces the unique sulfoxide group of actagardine, was also investigated in vitro.
Original language | English (US) |
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Pages (from-to) | 10966-10968 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 48 |
Issue number | 89 |
DOIs | |
State | Published - Oct 15 2012 |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Catalysis
- Ceramics and Composites
- General Chemistry
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry