Herbicide Metabolism: Crop Selectivity, Bioactivation, Weed Resistance, and Regulation

Vijay K. Nandula, Dean E. Riechers, Yurdagul Ferhatoglu, Michael Barrett, Stephen O. Duke, Franck E. Dayan, Alina Goldberg-Cavalleri, Catherine Tétard-Jones, David J. Wortley, Nawaporn Onkokesung, Melissa Brazier-Hicks, Robert Edwards, Todd Gaines, Satoshi Iwakami, Mithila Jugulam, Rong Ma

Research output: Contribution to journalArticle

Abstract

Several grass and broadleaf weed species around the world have evolved multiple-herbicide resistance at alarmingly increasing rates. Research on the biochemical and molecular resistance mechanisms of multiple-resistant weed populations indicate a prevalence of herbicide metabolism catalyzed by enzyme systems such as cytochrome P450 monooxygenases and glutathione S-transferases and, to a lesser extent, by glucosyl transferases. A symposium was conducted to gain an understanding of the current state of research on metabolic resistance mechanisms in weed species that pose major management problems around the world. These topics, as well as future directions of investigations that were identified in the symposium, are summarized herein. In addition, the latest information on selected topics such as the role of safeners in inducing crop tolerance to herbicides, selectivity to clomazone, glyphosate metabolism in crops and weeds, and bioactivation of natural molecules is reviewed.

Original languageEnglish (US)
Pages (from-to)149-175
Number of pages27
JournalWeed Science
Volume67
Issue number2
DOIs
StatePublished - Mar 1 2019

Keywords

  • Crop tolerance
  • cytochrome P450
  • glutathione
  • glutathione S -transferase
  • herbicide safener
  • natural phytotoxin
  • oxylipin

ASJC Scopus subject areas

  • Agronomy and Crop Science
  • Plant Science

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  • Cite this

    Nandula, V. K., Riechers, D. E., Ferhatoglu, Y., Barrett, M., Duke, S. O., Dayan, F. E., Goldberg-Cavalleri, A., Tétard-Jones, C., Wortley, D. J., Onkokesung, N., Brazier-Hicks, M., Edwards, R., Gaines, T., Iwakami, S., Jugulam, M., & Ma, R. (2019). Herbicide Metabolism: Crop Selectivity, Bioactivation, Weed Resistance, and Regulation. Weed Science, 67(2), 149-175. https://doi.org/10.1017/wsc.2018.88