Hemodynamic effects of calcium gluconate administered to conscious horses

Tamara L. Grubb, J. H. Foreman, G. John Benson, John C. Thurmon, William J. Tranquilli, Peter D. Constable, William O. Olson, Lloyd E. Davis

Research output: Contribution to journalArticlepeer-review


Calcium gluconate was administered to conscious horses at 3 different rates (0.1, 0.2, and 0.4 mg/kg/min for 15 minutes each). Serum calcium concentrations and parameters of cardiovascular function were evaluated. All 3 calcium administration rates caused marked increases in both ionized and total calcium concentrations, cardiac index, stroke index, and cardiac contractility (dP/dtmax). Mean arterial pressure and right atrial pressure were unchanged; heart rate decreased markedly during calcium administration. Ionized calcium concentration remained between 54% and 57% of total calcium concentration throughout the study. We conclude that calcium gluconate can safely be administered to conscious horses at 0.1 to 0.4 mg/kg/min and that administration will result in improved cardiac function.

Original languageEnglish (US)
Pages (from-to)401-404
Number of pages4
JournalJournal of veterinary internal medicine
Issue number6
StatePublished - 1996

ASJC Scopus subject areas

  • veterinary(all)


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