(equation presented) A series of tethered phenylene ethynylene oligomers, which undergo a solvent-dependent conformational transition from a random coil to a helix, has been synthesized. The use of trimethylsilyl ether protecting groups on the (+)-tartaric acid-derived tether results in the formation of helices with a large twist sense bias. In contrast, an isopropylidene ketal protecting group or no protecting group is not only ineffective at helical discrimination but may even inhibit helix formation.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Jan 27 2000|
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry