Abstract
(equation presented) A series of tethered phenylene ethynylene oligomers, which undergo a solvent-dependent conformational transition from a random coil to a helix, has been synthesized. The use of trimethylsilyl ether protecting groups on the (+)-tartaric acid-derived tether results in the formation of helices with a large twist sense bias. In contrast, an isopropylidene ketal protecting group or no protecting group is not only ineffective at helical discrimination but may even inhibit helix formation.
Original language | English (US) |
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Pages (from-to) | 135-138 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 2 |
Issue number | 2 |
DOIs | |
State | Published - Jan 27 2000 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry