Harmonic phase-dispersion microscope with a Mach-Zehnder interferometer

Andrew Ahn; Changhuei Yang; Adam Wax; Gabriel Popescu; Christopher Fang-Yen; Kamran Badizadegan; Ramachandra R. Dasari; Michael S. Feld

doi:10.1364/AO.44.001188

Harmonic phase-dispersion microscope with a Mach-Zehnder interferometer

Andrew Ahn, Changhuei Yang, Adam Wax, Gabriel Popescu, Christopher Fang-Yen, Kamran Badizadegan, Ramachandra R. Dasari, Michael S. Feld

Research output: Contribution to journal › Article › peer-review

Abstract

Harmonic phase-dispersion microscopy (PDM) is a new imaging technique in which contrast is provided by differences in refractive index at two harmonically related wavelengths. We report a new configuration of the harmonic phase-dispersion microscope in a Mach-Zehnder geometry as an instrument for imaging biological samples. Several improvements on the earlier design are demonstrated, including a single-pass configuration and acousto-optic modulators for generating the heterodyne signals without mechanical arm scanning. We demonstrate quantitative phase-dispersion images of test structures and biological samples.

Original language	English (US)
Pages (from-to)	1188-1190
Number of pages	3
Journal	Applied Optics
Volume	44
Issue number	7
DOIs	https://doi.org/10.1364/AO.44.001188
State	Published - Mar 1 2005
Externally published	Yes

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Engineering (miscellaneous)
Electrical and Electronic Engineering

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10.1364/AO.44.001188

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AU - Ahn, Andrew

AU - Yang, Changhuei

AU - Wax, Adam

AU - Popescu, Gabriel

AU - Fang-Yen, Christopher

AU - Badizadegan, Kamran

AU - Dasari, Ramachandra R.

AU - Feld, Michael S.

PY - 2005/3/1

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AB - Harmonic phase-dispersion microscopy (PDM) is a new imaging technique in which contrast is provided by differences in refractive index at two harmonically related wavelengths. We report a new configuration of the harmonic phase-dispersion microscope in a Mach-Zehnder geometry as an instrument for imaging biological samples. Several improvements on the earlier design are demonstrated, including a single-pass configuration and acousto-optic modulators for generating the heterodyne signals without mechanical arm scanning. We demonstrate quantitative phase-dispersion images of test structures and biological samples.

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Harmonic phase-dispersion microscope with a Mach-Zehnder interferometer

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