TY - JOUR
T1 - Handheld optical coherence tomography for clinical assessment of dental plaque and gingiva
AU - Won, Jungeun
AU - Huang, Pin Chieh
AU - Spillman, Darold R.
AU - Chaney, Eric J.
AU - Adam, Ralf
AU - Klukowska, Malgorzata
AU - Barkalifa, Ronit
AU - Boppart, Stephen A.
N1 - Publisher Copyright:
© The Authors.
PY - 2020/11/1
Y1 - 2020/11/1
N2 - Significance: Optical coherence tomography (OCT) offers high spatial resolution and contrast for imaging intraoral structures, yet few studies have investigated its clinical feasibility for dental plaque and gingiva imaging in vivo. Furthermore, the accessibility is often limited to anterior teeth due to bulky imaging systems and probes. Aim: A custom-designed, handheld probe-based, spectral-domain OCT system with an interchangeable attachment was developed to assess dental plaque and gingival health in a clinical setting. Approach: Healthy volunteers and subjects with gingivitis and sufficient plaque were recruited. The handheld OCT system was operated by trained dental hygienists to acquire images of dental plaque and gingiva at various locations and after one-week use of oral hygiene products. Results: The handheld OCT can access premolars, first molars, and lingual sides of teeth to visualize the plaque distribution. OCT intensity-based texture analysis revealed lower intensity from selected sites in subjects with gingivitis. The distribution of the dental plaque after one-week use of the oral hygiene products was compared, showing the capability of OCT as a longitudinal tracking tool. Conclusions: OCT has a strong potential to display and assess dental plaque and gingiva in a clinical setting. Meanwhile, technological challenges remain to perform systematic longitudinal tracking and comparative analyses.
AB - Significance: Optical coherence tomography (OCT) offers high spatial resolution and contrast for imaging intraoral structures, yet few studies have investigated its clinical feasibility for dental plaque and gingiva imaging in vivo. Furthermore, the accessibility is often limited to anterior teeth due to bulky imaging systems and probes. Aim: A custom-designed, handheld probe-based, spectral-domain OCT system with an interchangeable attachment was developed to assess dental plaque and gingival health in a clinical setting. Approach: Healthy volunteers and subjects with gingivitis and sufficient plaque were recruited. The handheld OCT system was operated by trained dental hygienists to acquire images of dental plaque and gingiva at various locations and after one-week use of oral hygiene products. Results: The handheld OCT can access premolars, first molars, and lingual sides of teeth to visualize the plaque distribution. OCT intensity-based texture analysis revealed lower intensity from selected sites in subjects with gingivitis. The distribution of the dental plaque after one-week use of the oral hygiene products was compared, showing the capability of OCT as a longitudinal tracking tool. Conclusions: OCT has a strong potential to display and assess dental plaque and gingiva in a clinical setting. Meanwhile, technological challenges remain to perform systematic longitudinal tracking and comparative analyses.
KW - biofilm
KW - dental plaque
KW - gingiva
KW - optical coherence tomography
KW - oral cavity
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U2 - 10.1117/1.JBO.25.11.116011
DO - 10.1117/1.JBO.25.11.116011
M3 - Article
C2 - 33244918
AN - SCOPUS:85096948327
SN - 1083-3668
VL - 25
JO - Journal of biomedical optics
JF - Journal of biomedical optics
IS - 11
M1 - 116011
ER -