TY - JOUR
T1 - H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa
AU - The H3ABioNet Consortium
AU - Mulder, Nicola J.
AU - Adebiyi, Ezekiel
AU - Alami, Raouf
AU - Benkahla, Alia
AU - Brandful, James
AU - Doumbia, Seydou
AU - Everett, Dean
AU - Fadlelmola, Faisal M.
AU - Gaboun, Fatima
AU - Gaseitsiwe, Simani
AU - Ghazal, Hassan
AU - Hazelhurst, Scott
AU - Hide, Winston
AU - Ibrahimi, Azeddine
AU - Fakim, Yasmina Jaufeerally
AU - Victor Jongeneel, C.
AU - Joubert, Fourie
AU - Kassim, Samar
AU - Kayondo, Jonathan
AU - Kumuthini, Judit
AU - Lyantagaye, Sylvester
AU - Makani, Julie
AU - Alzohairy, Ahmed Mansour
AU - Masiga, Daniel
AU - Moussa, Ahmed
AU - Nash, Oyekanmi
AU - Oukem-Boyer, Odile Ouwe Missi
AU - Owusu-Dabo, Ellis
AU - Panji, Sumir
AU - Patterton, Hugh
AU - Radouani, Fouzia
AU - Sadki, Khalid
AU - Seghrouchni, Fouad
AU - Bishop, Özlem Tastan
AU - Tiffin, Nicki
AU - Ulenga, Nzovu
AU - Adebiyi, Marion
AU - Ahmed, Azza E.
AU - Ahmed, Rehab I.
AU - Alearts, Maaike
AU - Alibi, Mohamed
AU - Aron, Shaun
AU - Baichoo, Shakuntala
AU - Bendou, Hocine
AU - Botha, Gerrit
AU - Brown, David
AU - Chimusa, Emile
AU - Fields, Chris
AU - Lapine, Dan
AU - Mainzer, Liudmila Sergeevna
N1 - Funding Information:
H3ABioNet is supported by the National Institutes of Health Common Fund (National Human Genome Research Institute) under grant number U41HG006941. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The authors thank all the Consortium members for their contributions to H3ABioNet activities. A full list of H3ABioNet Consortium members can be found at http://www.h3abionet.org/home/consortium.
Publisher Copyright:
© 2016 Mulder et al.
PY - 2016/2
Y1 - 2016/2
N2 - The application of genomics technologies to medicine and biomedical research is increasing in popularity, made possible by new high-throughput genotyping and sequencing technologies and improved data analysis capabilities. Some of the greatest genetic diversity among humans, animals, plants, and microbiota occurs in Africa, yet genomic research outputs from the continent are limited. The Human Heredity and Health in Africa (H3Africa) initiative was established to drive the development of genomic research for human health in Africa, and through recognition of the critical role of bioinformatics in this process, spurred the establishment of H3ABioNet, a pan-African bioinformatics network for H3Africa. The limitations in bioinformatics capacity on the continent have been a major contributory factor to the lack of notable outputs in highthroughput biology research. Although pockets of high-quality bioinformatics teams have existed previously, the majority of research institutions lack experienced faculty who can train and supervise bioinformatics students. H3ABioNet aims to address this dire need, specifically in the area of human genetics and genomics, but knock-on effects are ensuring this extends to other areas of bioinformatics. Here, we describe the emergence of genomics research and the development of bioinformatics in Africa through H3ABioNet.
AB - The application of genomics technologies to medicine and biomedical research is increasing in popularity, made possible by new high-throughput genotyping and sequencing technologies and improved data analysis capabilities. Some of the greatest genetic diversity among humans, animals, plants, and microbiota occurs in Africa, yet genomic research outputs from the continent are limited. The Human Heredity and Health in Africa (H3Africa) initiative was established to drive the development of genomic research for human health in Africa, and through recognition of the critical role of bioinformatics in this process, spurred the establishment of H3ABioNet, a pan-African bioinformatics network for H3Africa. The limitations in bioinformatics capacity on the continent have been a major contributory factor to the lack of notable outputs in highthroughput biology research. Although pockets of high-quality bioinformatics teams have existed previously, the majority of research institutions lack experienced faculty who can train and supervise bioinformatics students. H3ABioNet aims to address this dire need, specifically in the area of human genetics and genomics, but knock-on effects are ensuring this extends to other areas of bioinformatics. Here, we describe the emergence of genomics research and the development of bioinformatics in Africa through H3ABioNet.
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U2 - 10.1101/gr.196295.115
DO - 10.1101/gr.196295.115
M3 - Article
C2 - 26627985
AN - SCOPUS:84956889187
SN - 1088-9051
VL - 26
SP - 271
EP - 277
JO - Genome Research
JF - Genome Research
IS - 2
ER -