The study by Danforth et al. shows that gonadotropin-releasing hormone (GnRH) antagonists do not protect ovarian follicles from chemotherapy-induced damage and that GnRH antagonists alone reduce primordial follicle numbers in mice. This article discusses the strengths and limitations of the study by Danforth et al., as well as the potential mechanism of action of GnRH antagonists according to the literature.
|Original language||English (US)|
|Number of pages||4|
|Journal||Fertility and Sterility|
|State||Published - May 2005|
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynecology