Gold Nanorod/Fe3O4 nanoparticle "nano-pearl- necklaces" for simultaneous targeting, dual-mode imaging, and photothermal ablation of cancer cells

Chungang Wang, Jiji Chen, Tom Talavage, Joseph Irudayaraj

Research output: Contribution to journalArticle

Abstract

Gold and pearls: Multifunctional nanoparticles, each composed of a single, amine-modified gold nanorod, decorated with multiple "pearls" of Fe3O4 nanoparticles capped with carboxy groups, are prepared. Their effectiveness in simultaneous targeting, dual-mode imaging, and photothermal ablation of breast cancer cells is demonstrated.

Original languageEnglish (US)
Pages (from-to)2759-2763
Number of pages5
JournalAngewandte Chemie - International Edition
Volume48
Issue number15
DOIs
StatePublished - Mar 30 2009
Externally publishedYes

Keywords

  • Cell recognition
  • Gold
  • Imaging agents
  • Nanoparticles
  • Photothermal ablation

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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