Glyphosate inhibits rust diseases in glyphosate-resistant wheat and soybean

Paul C.C. Feng, G. James Baley, William P. Clinton, Greg J. Bunkers, Murtaza F. Alibhai, Timothy C. Paulitz, Kimberlee K. Kidwell

Research output: Contribution to journalArticlepeer-review


Glyphosate is a broad-spectrum herbicide used for the control of weeds in glyphosate-resistant crops. Glyphosate inhibits 5-enolpyruvyl shikimate 3-phosphate synthase, a key enzyme in the synthesis of aromatic amino acids in plants, fungi, and bacteria. Studies with glyphosate-resistant wheat have shown that glyphosate provided both preventive and curative activities against Puccinia striiformis f. sp. tritici and Puccinia triticina, which cause stripe and leaf rusts, respectively, in wheat. Growth-chamber studies demonstrated wheat rust control at multiple plant growth stages with a glyphosate spray dose typically recommended for weed control. Rust control was absent in formulation controls without glyphosate, dependent on systemic glyphosate concentrations in leaf tissues, and not mediated through induction of four common systemic acquired resistance genes. A field test with endemic stripe rust inoculum confirmed the activities of glyphosate pre- and postinfestation. Preliminary greenhouse studies also demonstrated that application of glyphosate in glyphosate-resistant soybeans suppressed Asian soybean rust, caused by Phakopsora pachyrhizi.

Original languageEnglish (US)
Pages (from-to)17290-17295
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Issue number48
StatePublished - Nov 29 2005
Externally publishedYes


  • Disease control
  • Phakopsora pachyrhizi
  • Puccinia striiformis f. Sp. Tritici
  • Puccinia triticina

ASJC Scopus subject areas

  • General


Dive into the research topics of 'Glyphosate inhibits rust diseases in glyphosate-resistant wheat and soybean'. Together they form a unique fingerprint.

Cite this