Glucose tolerance and insulin secretion in spontaneously hyperthyroid cats

M. Hoenig, M. E. Peterson, D. C. Ferguson

Research output: Contribution to journalArticlepeer-review


Glucose tolerance and insulin secretion after administration of a glucose load were determined in 11 clinically normal cats and 15 cats with spontaneous hyperthyroidism. In six hyperthyroid cats, a glucose tolerance test was repeated after treatment with radioactive iodine (131I). All cats had similar baseline glucose concentrations. However, the cats with hyperthyroidism had a significantly decreased glucose clearance, which was worse after treatment. Hyperthyroidism also caused a marked increase in basal and glucose-stimulated insulin secretion, which was not improved with treatment. It is concluded that hyperthyroidism in cats may lead to long-lasting alterations of glucose tolerance and insulin secretion which may not be reversed by treatment.

Original languageEnglish (US)
Pages (from-to)338-341
Number of pages4
JournalResearch in Veterinary Science
Issue number3
StatePublished - Nov 1992
Externally publishedYes

ASJC Scopus subject areas

  • veterinary(all)


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