TY - JOUR
T1 - Glucose tolerance and insulin secretion in spontaneously hyperthyroid cats
AU - Hoenig, M.
AU - Peterson, M. E.
AU - Ferguson, D. C.
N1 - Funding Information:
Acknowledgements This work was supported in part by the Companion Animal Research Fund, College of Veterinary Medicine, University of Georgia.
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1992/11
Y1 - 1992/11
N2 - Glucose tolerance and insulin secretion after administration of a glucose load were determined in 11 clinically normal cats and 15 cats with spontaneous hyperthyroidism. In six hyperthyroid cats, a glucose tolerance test was repeated after treatment with radioactive iodine (131I). All cats had similar baseline glucose concentrations. However, the cats with hyperthyroidism had a significantly decreased glucose clearance, which was worse after treatment. Hyperthyroidism also caused a marked increase in basal and glucose-stimulated insulin secretion, which was not improved with treatment. It is concluded that hyperthyroidism in cats may lead to long-lasting alterations of glucose tolerance and insulin secretion which may not be reversed by treatment.
AB - Glucose tolerance and insulin secretion after administration of a glucose load were determined in 11 clinically normal cats and 15 cats with spontaneous hyperthyroidism. In six hyperthyroid cats, a glucose tolerance test was repeated after treatment with radioactive iodine (131I). All cats had similar baseline glucose concentrations. However, the cats with hyperthyroidism had a significantly decreased glucose clearance, which was worse after treatment. Hyperthyroidism also caused a marked increase in basal and glucose-stimulated insulin secretion, which was not improved with treatment. It is concluded that hyperthyroidism in cats may lead to long-lasting alterations of glucose tolerance and insulin secretion which may not be reversed by treatment.
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U2 - 10.1016/0034-5288(92)90136-P
DO - 10.1016/0034-5288(92)90136-P
M3 - Article
C2 - 1465507
AN - SCOPUS:0026952776
SN - 0034-5288
VL - 53
SP - 338
EP - 341
JO - Research in Veterinary Science
JF - Research in Veterinary Science
IS - 3
ER -