Glomerulonephritis and Non-Hodgkin's Lymphoma: A Report of Two Cases and Review of the Literature

Raymond Rault, Jean L. Holley, Barbara F. Banner, Mohamed El-Shahawy

Research output: Contribution to journalArticlepeer-review


Two cases of glomerulonephritis associated with non-Hodgkin's lymphoma (NHL) are described. The first patient presented with the nephrotic syndrome and normal renal function, whereas the second suffered from recurrent acute renal failure together with a unique pattern of IgM deposition within glomerular capillaries. Our review of the literature suggests that this association, although rare, has been documented in a sufficient number of cases to show that it is more than coincidental. Whereas the most common renal lesion associated with Hodgkin's disease is minimal change disease, more advanced glomerular changes are found in the patients with NHL. This is reflected in the higher incidence of renal failure in the latter patients. Treatment of the lymphomas has been shown to result in improvement or even cure of the renal disease, although long-term follow-up is rarely available in the reported cases.

Original languageEnglish (US)
Pages (from-to)84-89
Number of pages6
JournalAmerican Journal of Kidney Diseases
Issue number1
StatePublished - 1992
Externally publishedYes


  • Glomerulonephritis
  • immunoglobulin M.
  • non-Hodgkin's lymphoma
  • renal failure

ASJC Scopus subject areas

  • Nephrology


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