Geometrical Effect in 2D Nanopores

Ke Liu, Martina Lihter, Aditya Sarathy, Sabina Caneva, Hu Qiu, Davide Deiana, Vasiliki Tileli, Duncan T.L. Alexander, Stephan Hofmann, Dumitru Dumcenco, Andras Kis, Jean Pierre Leburton, Aleksandra Radenovic

Research output: Contribution to journalArticlepeer-review


A long-standing problem in the application of solid-state nanopores is the lack of the precise control over the geometry of artificially formed pores compared to the well-defined geometry in their biological counterpart, that is, protein nanopores. To date, experimentally investigated solid-state nanopores have been shown to adopt an approximately circular shape. In this Letter, we investigate the geometrical effect of the nanopore shape on ionic blockage induced by DNA translocation using triangular h-BN nanopores and approximately circular molybdenum disulfide (MoS2) nanopores. We observe a striking geometry-dependent ion scattering effect, which is further corroborated by a modified ionic blockage model. The well-acknowledged ionic blockage model is derived from uniform ion permeability through the 2D nanopore plane and hemisphere like access region in the nanopore vicinity. On the basis of our experimental results, we propose a modified ionic blockage model, which is highly related to the ionic profile caused by geometrical variations. Our findings shed light on the rational design of 2D nanopores and should be applicable to arbitrary nanopore shapes.

Original languageEnglish (US)
Pages (from-to)4223-4230
Number of pages8
JournalNano letters
Issue number7
StatePublished - Jul 12 2017


  • 2D materials
  • Solid-state nanopores
  • hexagonal boron nitride (h-BN)
  • high-resolution transmission electron microscopy (HRTEM)
  • ion transport
  • molybdenum disulfide (MoS)

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering


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