TY - JOUR
T1 - Genomics tools in microbial food safety
AU - Stasiewicz, Matthew J.
AU - den Bakker, Henk C.
AU - Wiedmann, Martin
N1 - Publisher Copyright:
© 2015 Elsevier Ltd.
PY - 2015/8/1
Y1 - 2015/8/1
N2 - Genomics tools, and specifically whole-genome sequencing (WGS) methods, are rapidly transforming food safety, specifically through improved outbreak detection. In the U.S., whole genome sequencing of all human clinical Listeria monocytogenes isolates has been performed since 2013; isolates from foods and food processing plants obtained by regulatory agencies are also routinely characterized by WGS. Routine application of WGS appears to increase the number of listeriosis outbreaks that are detected and traced back to specific food sources. While rapidly improving WGS technologies have driven use of omics tools in food safety over the last 5-7 years, improved analytic methods will drive effective application of omics tools including genomics, transcriptomics, proteomics, and metabolomics over the next few years.
AB - Genomics tools, and specifically whole-genome sequencing (WGS) methods, are rapidly transforming food safety, specifically through improved outbreak detection. In the U.S., whole genome sequencing of all human clinical Listeria monocytogenes isolates has been performed since 2013; isolates from foods and food processing plants obtained by regulatory agencies are also routinely characterized by WGS. Routine application of WGS appears to increase the number of listeriosis outbreaks that are detected and traced back to specific food sources. While rapidly improving WGS technologies have driven use of omics tools in food safety over the last 5-7 years, improved analytic methods will drive effective application of omics tools including genomics, transcriptomics, proteomics, and metabolomics over the next few years.
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U2 - 10.1016/j.cofs.2015.06.002
DO - 10.1016/j.cofs.2015.06.002
M3 - Review article
AN - SCOPUS:84933040261
SN - 2214-7993
VL - 4
SP - 105
EP - 110
JO - Current Opinion in Food Science
JF - Current Opinion in Food Science
ER -