TY - JOUR
T1 - Genome-Wide Association Study of Meat Quality Traits in Nellore Cattle
AU - Magalhã, Ana F.B.
AU - De Camargo, Gregório M.F.
AU - Junior Fernandes, Gerardo A.
AU - Gordo, Daniel G.M.
AU - Tonussi, Rafael L.
AU - Costa, Raphael B.
AU - Espigolan, Rafael
AU - De Silva, Rafael M.O.
AU - Bresolin, Tiago
AU - De Andrade, Willian B.F.
AU - Takada, Luciana
AU - Feitosa, Fabieli L.B.
AU - Baldi, Fernando
AU - Carvalheiro, Roberto
AU - Chardulo, Luis A.L.
AU - De Albuquerque, Lucia G.
N1 - Publisher Copyright:
© 2016 Magalhães et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2016/6
Y1 - 2016/6
N2 - The objective of this study was to identify genomic regions that are associated with meat quality traits in the Nellore breed. Nellore steers were finished in feedlots and slaughtered at a commercial slaughterhouse. This analysis included 1,822 phenotypic records of tenderness and 1,873 marbling records. After quality control, 1,630 animals genotyped for tenderness, 1,633 animals genotyped for marbling, and 369,722 SNPs remained. The results are reported as the proportion of variance explained by windows of 150 adjacent SNPs. Only windows with largest effects were considered. The genomic regions were located on chromosomes 5, 15, 16 and 25 for marbling and on chromosomes 5, 7, 10, 14 and 21 for tenderness. These windows explained 3,89% and 3,80% of the additive genetic variance for marbling and tenderness, respectively. The genes associated with the traits are related to growth, muscle development and lipid metabolism. The study of these genes in Nellore cattle is the first step in the identification of causal mutations that will contribute to the genetic evaluation of the breed.
AB - The objective of this study was to identify genomic regions that are associated with meat quality traits in the Nellore breed. Nellore steers were finished in feedlots and slaughtered at a commercial slaughterhouse. This analysis included 1,822 phenotypic records of tenderness and 1,873 marbling records. After quality control, 1,630 animals genotyped for tenderness, 1,633 animals genotyped for marbling, and 369,722 SNPs remained. The results are reported as the proportion of variance explained by windows of 150 adjacent SNPs. Only windows with largest effects were considered. The genomic regions were located on chromosomes 5, 15, 16 and 25 for marbling and on chromosomes 5, 7, 10, 14 and 21 for tenderness. These windows explained 3,89% and 3,80% of the additive genetic variance for marbling and tenderness, respectively. The genes associated with the traits are related to growth, muscle development and lipid metabolism. The study of these genes in Nellore cattle is the first step in the identification of causal mutations that will contribute to the genetic evaluation of the breed.
UR - http://www.scopus.com/inward/record.url?scp=84977569035&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84977569035&partnerID=8YFLogxK
U2 - 10.1371/journal.pone.0157845
DO - 10.1371/journal.pone.0157845
M3 - Article
C2 - 27359122
AN - SCOPUS:84977569035
SN - 1932-6203
VL - 11
JO - PloS one
JF - PloS one
IS - 6
M1 - e0157845
ER -