Genistein inhibits proliferation and induces senescence in neonatal mouse pituitary gland explant cultures

Keyphrases

• Apoptosis 8%
• B-cell Lymphoma 2 (Bcl-2) 8%
• CDKN1A 8%
• Cell Cycle Dynamics 8%
• Cell Cycle Exit 8%
• Cellular Senescence 8%
• Cyclin B1 8%
• Cyclin-dependent Kinase Inhibitor 8%
• Endocrine Cells 8%
• Endocrine Disruption 8%
• Endocrine Effects 8%
• Endocrine Signaling 8%
• Estradiol 8%
• Estrogen Receptor 8%
• Estrogen Receptor Signaling 8%
• Explant Culture 100%
• Genistein 100%
• Glands 8%
• Immunostaining 8%
• Inhibits Proliferation 100%
• Isoflavones 8%
• MKI67 8%
• MRNA Expression 8%
• MRNA Level 8%
• Neonatal Development 8%
• Neonatal Mice 100%
• Neonatal Period 8%
• Phosphohistone H3 8%
• Pituitary 25%
• Pituitary Gland 100%
• Proper Number 8%
• Protein Changes 8%
• Regulated Genes 8%
• Senescence 100%
• Signaling Hub 8%
• Soy Formula 8%
• β-Galactosidase (β-Gal) 8%

Biochemistry, Genetics and Molecular Biology

• Cell Cycle 8%
• Cell Cycle Exit 8%
• Cyclin B1 8%
• Cyclin-Dependent Kinase 8%
• Dynamics 8%
• Endocrine Cell 8%
• Estradiol 8%
• Estrogen Receptor 16%
• Explant 100%
• Galactosidase 8%
• Genistein 100%
• Histone H3 8%
• Immunostaining 8%
• Isoflavone 8%
• Messenger RNA 50%
• Newborn Period 8%
• P21 16%
• Perinatal Development 8%
• Programmed Cell Death 8%

Pharmacology, Toxicology and Pharmaceutical Science

• Cyclin B1 8%
• Cyclin Dependent Kinase Inhibitor 8%
• Diethylstilbestrol 8%
• Estrogen Receptor 16%
• Galactosidase 8%
• Genistein 100%
• Histone H3 8%
• Isoflavone 8%
• Messenger RNA 50%