General method for forming micrometer-scale lateral chemical gradients in polymer brushes

Hyung Jun Koo, Kristopher V. Waynant, Chunjie Zhang, Richard T. Haasch, Paul V. Braun

Research output: Contribution to journalArticlepeer-review

Abstract

We report a general diffusion based method to form micrometer-scale lateral chemical gradients in polymer brushes via selective alkylation. A quaternized brush gradient is derived from a concentration gradient of alkylating agent formed by diffusion in permeable media around a microchannel carrying the alkylating agent. Polymer brushes containing both charge and aromatic gradients are formed using the alkylating agents, methyl iodide and benzyl bromide, respectively. The gradients are quantitatively characterized by confocal Raman spectroscopy and qualitatively by fluorescence microscopy. The length and gradient strength can be controlled by varying the diffusion time, concentrations, and solvents of the alkylating agent solutions. This microfluidic brush gradient generation method enables formation of 2-D chemical potential gradients with a diversity of shapes.

Original languageEnglish (US)
Pages (from-to)2678-2683
Number of pages6
JournalChemistry of Materials
Volume26
Issue number8
DOIs
StatePublished - Apr 22 2014

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)
  • Materials Chemistry

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