Functional compromises among pH tolerance, site specificity, and sequence tolerance for a DNA-hydrolyzing deoxyribozyme

Keyphrases

• Deoxyribozyme 100%
• Site Specificity 100%
• PH Tolerance 100%
• Functional Compromise 100%
• DNA Substrates 60%
• DNA Cleavage 60%
• Sequence Specificity 40%
• Watson-Crick Complementarity 40%
• Mn2+ 20%
• Zn2+ 20%
• Single-stranded DNA (ssDNA) 20%
• Phosphate 20%
• Cleavage Site 20%
• In Vitro Selection 20%
• Watson-Crick 20%
• Rate Enhancement 20%
• Hydroxyl 20%
• Cleavage Rate 20%
• Hydrolysis Reaction 20%
• Recognition Site 20%
• Optimum pH 20%
• Ongoing Development 20%
• Uncatalyzed 20%
• Phosphodiester Bond 20%
• In Vitro Evolution 20%
• DNA Hydrolysis 20%
• Deselection 20%
• Broad pH 20%

Biochemistry, Genetics and Molecular Biology

• Catalytic DNA 100%
• Enzymatic Hydrolysis 75%
• DNA Cleavage 75%
• in Vitro Selection 25%
• Single-Stranded DNA 25%
• Phosphodiester Bond 25%

Immunology and Microbiology

• DNA Cleavage 100%
• Hydrolysis 66%
• in Vitro Selection 33%