From ship hulls to contact lenses: Repression of protein adsorption and the puzzle of PEO

Avraham Halperin, Deborah E Leckband

Research output: Contribution to journalArticle

Abstract

Poly(ethyleneoxyde) (PEO) is utilized for repression of protein adsorption in a variety of biomedical and technological situations. The customary analysis of the interactions between proteins and PEO models the PEO as a simple polymer comprising monomers having a single state. We review the evidence suggesting that such analysis should allow for multiple and interconverting monomeric states.

Original languageEnglish (US)
Pages (from-to)1171-1178
Number of pages8
JournalComptes Rendus de l'Academie des Sciences - Series IV: Physics, Astrophysics
Volume1
Issue number9
DOIs
StatePublished - Nov 2000

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ship hulls
contact lenses
proteins
adsorption
monomers
polymers
interactions

Keywords

  • Adsorption
  • Grafted polymer
  • Poly(ethyleneoxide)
  • Protein

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

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abstract = "Poly(ethyleneoxyde) (PEO) is utilized for repression of protein adsorption in a variety of biomedical and technological situations. The customary analysis of the interactions between proteins and PEO models the PEO as a simple polymer comprising monomers having a single state. We review the evidence suggesting that such analysis should allow for multiple and interconverting monomeric states.",
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KW - Protein

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