Abstract
This paper reviews the interdisciplinary work performed in our group in recent years to develop micro-integrated devices to characterize biological entities. We present the use of electrical and mechanically based phenomena to perform characterization and various functions needed for integrated biochips. One sub-system takes advantage of the dielectrophoretic effect to sort and concentrate cells within a micro-fluidic biochip. Another sub-system measures impedance changes produced by the metabolic activity of cells to determine their viability. A third sub-system is used to detect the mass of bacteria as they bind to micro-mechanical silicon cantilevers. These devices with an electronic signal output can be very useful in producing practical systems for rapid detection and characterization of cells for a wide variety of applications in the food safety and health diagnostics industries.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 117-124 |
| Number of pages | 8 |
| Journal | Materials Research Society Symposium - Proceedings |
| Volume | 773 |
| DOIs | |
| State | Published - 2003 |
| Externally published | Yes |
| Event | Biomicroelectromechanical Systems (BioMEMS) - San Francisco, CA, United States Duration: Apr 22 2003 → Apr 25 2003 |
ASJC Scopus subject areas
- Materials Science(all)
- Condensed Matter Physics
- Mechanics of Materials
- Mechanical Engineering