Fractional derivative models for ultrasonic characterization of polymer and breast tissue viscoelasticity

Cecile Coussot, Sureshkumar Kalyanam, Rebecca Yapp, Michael Insana

Research output: Contribution to journalArticle

Abstract

The viscoelastic response of hydropolymers, which include glandular breast tissues, may be accurately characterized for some applications with as few as 3 rheological parameters by applying the Kelvin-Voigt fractional derivative (KVFD) modeling approach. We describe a technique for ultrasonic imaging of KVFD parameters in media undergoing unconfined, quasi-static, uniaxial compression. We analyze the KVFD parameter values in simulated and experimental echo data acquired from phantoms and show that the KVFD parameters may concisely characterize the viscoelastic properties of hydropolymers. We then interpret the KVFD parameter values for normal and cancerous breast tissues and hypothesize that this modeling approach may ultimately be applied to tumor differentiation.

Original languageEnglish (US)
Article number4815301
Pages (from-to)715-725
Number of pages11
JournalIEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Volume56
Issue number4
DOIs
StatePublished - Apr 2009

ASJC Scopus subject areas

  • Instrumentation
  • Acoustics and Ultrasonics
  • Electrical and Electronic Engineering

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