Fourier transform light scattering of biological structure and dynamics

Huafeng Ding; Ethan Berl; Zhuo Wang; Larry J. Millet; Martha U. Gillette; Jianming Liu; Marni Boppart; Gabriel Popescu

doi:10.1109/JSTQE.2009.2034752

Fourier transform light scattering of biological structure and dynamics

Huafeng Ding, Ethan Berl, Zhuo Wang, Larry J. Millet, Martha U. Gillette, Jianming Liu, Marni Boppart, Gabriel Popescu

Research output: Contribution to journal › Review article › peer-review

Abstract

We review the principle and application of Fourier transform light scattering (FTLS), a new technique developed in our laboratory to study static and dynamic light scattering (DLS) from the biological tissues and live cells. The results demonstrate that FTLS has significant benefits over existing light scattering techniques in terms of sensitivity and resolution. We anticipate that FTLS will set the basis for disease diagnosis based on the intrinsic tissue optical properties and provide an efficient tool for quantifying cell structures and dynamics.

Original language	English (US)
Article number	5443519
Pages (from-to)	909-918
Number of pages	10
Journal	IEEE Journal on Selected Topics in Quantum Electronics
Volume	16
Issue number	4
DOIs	https://doi.org/10.1109/JSTQE.2009.2034752
State	Published - Jul 2010

Keywords

Cells
Fourier transform light scattering (FTLS)
light scattering
phase
quantitative phase imaging (QPI)
tissue

ASJC Scopus subject areas

Electrical and Electronic Engineering
Atomic and Molecular Physics, and Optics

Online availability

10.1109/JSTQE.2009.2034752

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title = "Fourier transform light scattering of biological structure and dynamics",

abstract = "We review the principle and application of Fourier transform light scattering (FTLS), a new technique developed in our laboratory to study static and dynamic light scattering (DLS) from the biological tissues and live cells. The results demonstrate that FTLS has significant benefits over existing light scattering techniques in terms of sensitivity and resolution. We anticipate that FTLS will set the basis for disease diagnosis based on the intrinsic tissue optical properties and provide an efficient tool for quantifying cell structures and dynamics.",

keywords = "Cells, Fourier transform light scattering (FTLS), light scattering, phase, quantitative phase imaging (QPI), tissue",

author = "Huafeng Ding and Ethan Berl and Zhuo Wang and Millet, {Larry J.} and Gillette, {Martha U.} and Jianming Liu and Marni Boppart and Gabriel Popescu",

note = "Funding Information: Manuscript received August 2, 2009; revised September 15, 2009; accepted September 15, 2009 . Date of publication April 5, 2010; date of current version August 6, 2010. The work of G. Popescu was supported in part by the National Science Foundation (CAREER 08-46660) and Grainger Foundation.",

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doi = "10.1109/JSTQE.2009.2034752",

language = "English (US)",

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AU - Ding, Huafeng

AU - Berl, Ethan

AU - Wang, Zhuo

AU - Millet, Larry J.

AU - Gillette, Martha U.

AU - Liu, Jianming

AU - Boppart, Marni

AU - Popescu, Gabriel

N1 - Funding Information: Manuscript received August 2, 2009; revised September 15, 2009; accepted September 15, 2009 . Date of publication April 5, 2010; date of current version August 6, 2010. The work of G. Popescu was supported in part by the National Science Foundation (CAREER 08-46660) and Grainger Foundation.

PY - 2010/7

Y1 - 2010/7

N2 - We review the principle and application of Fourier transform light scattering (FTLS), a new technique developed in our laboratory to study static and dynamic light scattering (DLS) from the biological tissues and live cells. The results demonstrate that FTLS has significant benefits over existing light scattering techniques in terms of sensitivity and resolution. We anticipate that FTLS will set the basis for disease diagnosis based on the intrinsic tissue optical properties and provide an efficient tool for quantifying cell structures and dynamics.

AB - We review the principle and application of Fourier transform light scattering (FTLS), a new technique developed in our laboratory to study static and dynamic light scattering (DLS) from the biological tissues and live cells. The results demonstrate that FTLS has significant benefits over existing light scattering techniques in terms of sensitivity and resolution. We anticipate that FTLS will set the basis for disease diagnosis based on the intrinsic tissue optical properties and provide an efficient tool for quantifying cell structures and dynamics.

KW - Cells

KW - Fourier transform light scattering (FTLS)

KW - light scattering

KW - phase

KW - quantitative phase imaging (QPI)

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Fourier transform light scattering of biological structure and dynamics

Abstract

Keywords

ASJC Scopus subject areas

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