Abstract

Fourier transform light scattering (FTLS) has been recently developed as a novel, ultrasensitive method for studying light scattering from inhomogeneous and dynamic structures. FTLS relies on quantifying the optical phase and amplitude associated with a coherent image field and propagating it numerically to the scattering plane. In this paper, we review the principle and applications of FTLS to static and dynamic light scattering from biological tissues and live cells. Compared with other existing light scattering techniques, FTLS has significant benefits of high sensitivity, speed, and angular resolution. We anticipate that FTLS will set the basis for disease diagnosis based on intrinsic tissue optical properties and provide an efficient tool for quantifying cell structures and dynamics.

Original languageEnglish (US)
Pages (from-to)2501-2511
Number of pages11
JournalJournal of Computational and Theoretical Nanoscience
Volume7
Issue number12
DOIs
StatePublished - Dec 1 2010

Fingerprint

Light Scattering
Light scattering
Fourier transform
Fourier transforms
light scattering
Tissue
Cell
cells
Dynamic Light Scattering
Biological Tissue
Dynamic light scattering
Optical Properties
angular resolution
Optical properties
Scattering
optical properties
sensitivity
scattering

Keywords

  • Cells
  • Fourier transform light scattering
  • Phase
  • Quantitative phase microscopy
  • Scattering
  • Tissue

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Electrical and Electronic Engineering
  • Materials Science(all)
  • Computational Mathematics
  • Chemistry(all)

Cite this

Fourier transform light scattering (FTLS) of cells and tissues. / Ding, Huafeng; Wang, Zhuo; Nguyen, Freddy T.; Boppart, Stephen A.; Millet, Larry J.; Gillette, Martha U.; Liu, Jianming; Boppart, Marni D.; Popescu, Gabriel.

In: Journal of Computational and Theoretical Nanoscience, Vol. 7, No. 12, 01.12.2010, p. 2501-2511.

Research output: Contribution to journalReview article

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AU - Ding, Huafeng

AU - Wang, Zhuo

AU - Nguyen, Freddy T.

AU - Boppart, Stephen A.

AU - Millet, Larry J.

AU - Gillette, Martha U.

AU - Liu, Jianming

AU - Boppart, Marni D.

AU - Popescu, Gabriel

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