Fourier transform infrared (Ft-Ir) spectroscopic imaging for solid tumor histopathology

Sreeradha Biswas, Michael J. Walsh, Rohit Bhargava

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Fourier transform infrared (FT-IR) spectroscopic imaging has shown great promise in becoming a powerful tool in cytology and histopathology. Applications for cancer diagnoses in solid tumors are especially attractive as samples are spatially complex and involve myriad molecular changes whereas there are many shortcomings in current clinical practice that can be addressed. Here we review the current state of the art in applying FT-IR imaging for analyzing solid tumors. We focus on instrumentation that is relatively new, emerging fundamental understanding gained by new theoretical advances, data analysis and selected, illustrative applications in cancer histopathology.

Original languageEnglish (US)
Title of host publicationChallenges and Advances in Computational Chemistry and Physics
PublisherSpringer
Pages475-504
Number of pages30
DOIs
StatePublished - Jan 1 2014

Publication series

NameChallenges and Advances in Computational Chemistry and Physics
Volume14
ISSN (Print)2542-4491
ISSN (Electronic)2542-4483

Fingerprint

Tumors
Fourier transforms
tumors
cancer
cytology
Cytology
Infrared radiation
Imaging techniques
Infrared imaging
emerging

Keywords

  • Bayesian classification
  • Breast
  • Cancer pathology
  • Discrete frequency
  • Fourier transform infrared imaging
  • Histopathology
  • Instrumentation
  • Lasers
  • Metrics
  • Prostate
  • Statistical pattern recognition
  • Theory
  • Tissue imaging

ASJC Scopus subject areas

  • Computer Science Applications
  • Chemistry (miscellaneous)
  • Physics and Astronomy (miscellaneous)

Cite this

Biswas, S., Walsh, M. J., & Bhargava, R. (2014). Fourier transform infrared (Ft-Ir) spectroscopic imaging for solid tumor histopathology. In Challenges and Advances in Computational Chemistry and Physics (pp. 475-504). (Challenges and Advances in Computational Chemistry and Physics; Vol. 14). Springer. https://doi.org/10.1007/978-94-007-7832-0_16

Fourier transform infrared (Ft-Ir) spectroscopic imaging for solid tumor histopathology. / Biswas, Sreeradha; Walsh, Michael J.; Bhargava, Rohit.

Challenges and Advances in Computational Chemistry and Physics. Springer, 2014. p. 475-504 (Challenges and Advances in Computational Chemistry and Physics; Vol. 14).

Research output: Chapter in Book/Report/Conference proceedingChapter

Biswas, S, Walsh, MJ & Bhargava, R 2014, Fourier transform infrared (Ft-Ir) spectroscopic imaging for solid tumor histopathology. in Challenges and Advances in Computational Chemistry and Physics. Challenges and Advances in Computational Chemistry and Physics, vol. 14, Springer, pp. 475-504. https://doi.org/10.1007/978-94-007-7832-0_16
Biswas S, Walsh MJ, Bhargava R. Fourier transform infrared (Ft-Ir) spectroscopic imaging for solid tumor histopathology. In Challenges and Advances in Computational Chemistry and Physics. Springer. 2014. p. 475-504. (Challenges and Advances in Computational Chemistry and Physics). https://doi.org/10.1007/978-94-007-7832-0_16
Biswas, Sreeradha ; Walsh, Michael J. ; Bhargava, Rohit. / Fourier transform infrared (Ft-Ir) spectroscopic imaging for solid tumor histopathology. Challenges and Advances in Computational Chemistry and Physics. Springer, 2014. pp. 475-504 (Challenges and Advances in Computational Chemistry and Physics).
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