A dynamic binding mechanism allows the association of dumbbell-shaped ligand 2 with helical folded oligo(m-phenyleneethynylene)s 1 (see schematic representation). Association constants are oligomer length specific, with a maximum value for the icosamer and docosamer. These oligomers have helical conformations that are highly shape-complementary to 1; shorter and longer oligomers exhibit association constants roughly an order of magnitude smaller.
|Original language||English (US)|
|Number of pages||4|
|Journal||Angewandte Chemie - International Edition|
|State||Published - Jan 18 2002|
- Host-guest systems
- Molecular recognition
ASJC Scopus subject areas