Foals raised on pasture with or without daily pyrantel tartrate feed additive: Comparison of parasite burdens and host responses following experimental challenge with large and small strongyle larvae

C. M. Monahan, M. R. Chapman, H. W. Taylor, D. D. French, T. R. Klei

Research output: Contribution to journalArticlepeer-review

Abstract

Three groups of foals were raised under different management programs in this study: Group 1 (n = 6) and Group 2 (n = 6) were raised with their dams on pasture; Group 3 foals (n = 5) were raised under parasite-free conditions. Mares and foals of Group 1 received daily pyrantel tartrate (PT) treatment with their pelleted feed ration, whereas mares and foals of Groups 2 and 3 received only the pelleted ration. Pasture-reared foals were weaned and moved to a heavily contaminated pasture for 5 weeks. Group 1 foals continued to receive daily PT treatment whereas Group 2 foals received only the pelleted feed ration. Following this period, all foals were moved into box stalls. Half of each group was challenged with 103 Strongylus vulgaris infective third-stage larvae (L3), 5 x 103 Strongylus edentatus L3 and 103 mixed cyathostome L3; the remaining half served as unchallenged controls. Necropsy examinations were performed 6-week post-challenge for evaluation of parasite burdens and lesions. Daily PT treatment of Group I reduced the patent cyathostome infections of both mares and foals and was effective in reducing pasture burdens of infective larvae. Daily treatment of Group 1 foals during weaning continued to suppress EPG levels; however, it did not prevent large strongyle infections during the weaning period. Group 1 foals were more sensitive to challenge than Group 2 foals, which did not exhibit any post- challenge disturbances. Group 1 foals were equally susceptible to challenge as parasite-free foals.

Original languageEnglish (US)
Pages (from-to)277-289
Number of pages13
JournalVeterinary parasitology
Volume73
Issue number3-4
DOIs
StatePublished - Dec 31 1997
Externally publishedYes

Keywords

  • Anthelmintic treatment
  • Chemotherapy
  • Cyathostominae
  • Encysted larvae
  • Equine parasites
  • Large strongyles
  • Pyrantel tartrate
  • Small strongyles
  • Strongylus vulgaris

ASJC Scopus subject areas

  • Parasitology
  • General Veterinary

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