TY - JOUR
T1 - FlyFactorSurvey
T2 - A database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system
AU - Zhu, Lihua Julie
AU - Christensen, Ryan G.
AU - Kazemian, Majid
AU - Hull, Christopher J.
AU - Enuameh, Metewo Selase
AU - Basciotta, Matthew D.
AU - Brasefield, Jessie A.
AU - Zhu, Cong
AU - Asriyan, Yuna
AU - Lapointe, David S.
AU - Sinha, Saurabh
AU - Wolfe, Scot A.
AU - Brodsky, Michael H.
N1 - The characterization and analysis of transcription factor binding specificities, for the construction of the database and website. Funding for open access charge: National Human Genome Research Institute of the National Institutes of Health (R01 HG004744-01 to M.H.B. and S.A.W.).
PY - 2011/1
Y1 - 2011/1
N2 - FlyFactorSurvey (http://pgfe.umassmed.edu/ TFDBS/) is a database of DNA binding specificities for Drosophila transcription factors (TFs) primarily determined using the bacterial one-hybrid system. The database provides community access to over 400 recognition motifs and position weight matrices for over 200 TFs, including many unpublished motifs. Search tools and flat file downloads are provided to retrieve binding site information (as sequences, matrices and sequence logos) for individual TFs, groups of TFs or for all TFs with characterized binding specificities. Linked analysis tools allow users to identify motifs within our database that share similarity to a query matrix or to view the distribution of occurrences of an individual motif throughout the Drosophila genome. Together, this database and its associated tools provide computational and experimental biologists with resources to predict interactions between Drosophila TFs and target cis-regulatory sequences.
AB - FlyFactorSurvey (http://pgfe.umassmed.edu/ TFDBS/) is a database of DNA binding specificities for Drosophila transcription factors (TFs) primarily determined using the bacterial one-hybrid system. The database provides community access to over 400 recognition motifs and position weight matrices for over 200 TFs, including many unpublished motifs. Search tools and flat file downloads are provided to retrieve binding site information (as sequences, matrices and sequence logos) for individual TFs, groups of TFs or for all TFs with characterized binding specificities. Linked analysis tools allow users to identify motifs within our database that share similarity to a query matrix or to view the distribution of occurrences of an individual motif throughout the Drosophila genome. Together, this database and its associated tools provide computational and experimental biologists with resources to predict interactions between Drosophila TFs and target cis-regulatory sequences.
UR - https://www.scopus.com/pages/publications/78651321628
UR - https://www.scopus.com/pages/publications/78651321628#tab=citedBy
U2 - 10.1093/nar/gkq858
DO - 10.1093/nar/gkq858
M3 - Article
C2 - 21097781
AN - SCOPUS:78651321628
SN - 0305-1048
VL - 39
SP - D111-D117
JO - Nucleic acids research
JF - Nucleic acids research
IS - SUPPL. 1
ER -