Fidelity in the supramolecular assembly of triply and quadruply hydrogen-bonded complexes

Eric M. Todd, Jordan R. Quinn, Taiho Park, Steven C. Zimmerman

Research output: Contribution to journalArticlepeer-review

Abstract

Advancements in self-assembly and nanotechnology will require multiple assembly "codes" to be executed simultaneously. At the molecular level this will require fidelity or orthogonality in molecular recognition events. To explore the limits of orthogonal assembly, association constants (K assoc) and dimerization constants (Kdimer) were measured with a known series of matched and mismatched recognition units in chloroform. Using the available complexation constants, fidelity, defined as [concentration of desired complexes]/[all complexes], was modeled for several component mixtures allowing general conditions for high fidelity assembly to be elucidated.

Original languageEnglish (US)
Pages (from-to)381-389
Number of pages9
JournalIsrael Journal of Chemistry
Volume45
Issue number3
DOIs
StatePublished - 2005

ASJC Scopus subject areas

  • Chemistry(all)

Fingerprint Dive into the research topics of 'Fidelity in the supramolecular assembly of triply and quadruply hydrogen-bonded complexes'. Together they form a unique fingerprint.

Cite this