Female antiandrogens

Radwa Barakat, Che Myong J. Ko

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Androgens are synthesized in the ovary and other local tissues in females and play important roles in regulating development and function of the reproductive organs. Antiandrogens are a class of drugs that either inhibit androgen production or block the androgen receptor signaling, preventing androgens from mediating their biological effects in the body. In females, antiandrogens are often used to treat symptoms that are caused by hyperandrogenism, such as acne, hirsutism, and seborrhea. However, unintended exposures to antiandrogens often have adverse effects on the development and function of reproductive organs. This review discusses the impacts of antiandrogens on the female reproductive systems, focusing on environmental endocrine disruptors.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Reproduction
PublisherElsevier
Pages748-752
Number of pages5
ISBN (Electronic)9780128151457
DOIs
StatePublished - Jan 1 2018

Keywords

  • Androgens
  • Antiandrogens
  • Endocrine disruptor
  • Female reproduction

ASJC Scopus subject areas

  • General Medicine

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