Female antiandrogens

Radwa Barakat; Che Myong J. Ko

doi:10.1016/B978-0-12-801238-3.64415-X

Female antiandrogens

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Androgens are synthesized in the ovary and other local tissues in females and play important roles in regulating development and function of the reproductive organs. Antiandrogens are a class of drugs that either inhibit androgen production or block the androgen receptor signaling, preventing androgens from mediating their biological effects in the body. In females, antiandrogens are often used to treat symptoms that are caused by hyperandrogenism, such as acne, hirsutism, and seborrhea. However, unintended exposures to antiandrogens often have adverse effects on the development and function of reproductive organs. This review discusses the impacts of antiandrogens on the female reproductive systems, focusing on environmental endocrine disruptors.

Original language	English (US)
Title of host publication	Encyclopedia of Reproduction
Publisher	Elsevier
Pages	748-752
Number of pages	5
ISBN (Electronic)	9780128151457
DOIs	https://doi.org/10.1016/B978-0-12-801238-3.64415-X
State	Published - Jan 1 2018

Keywords

Androgens
Antiandrogens
Endocrine disruptor
Female reproduction

ASJC Scopus subject areas

Medicine(all)

Online availability

10.1016/B978-0-12-801238-3.64415-X

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abstract = "Androgens are synthesized in the ovary and other local tissues in females and play important roles in regulating development and function of the reproductive organs. Antiandrogens are a class of drugs that either inhibit androgen production or block the androgen receptor signaling, preventing androgens from mediating their biological effects in the body. In females, antiandrogens are often used to treat symptoms that are caused by hyperandrogenism, such as acne, hirsutism, and seborrhea. However, unintended exposures to antiandrogens often have adverse effects on the development and function of reproductive organs. This review discusses the impacts of antiandrogens on the female reproductive systems, focusing on environmental endocrine disruptors.",

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AB - Androgens are synthesized in the ovary and other local tissues in females and play important roles in regulating development and function of the reproductive organs. Antiandrogens are a class of drugs that either inhibit androgen production or block the androgen receptor signaling, preventing androgens from mediating their biological effects in the body. In females, antiandrogens are often used to treat symptoms that are caused by hyperandrogenism, such as acne, hirsutism, and seborrhea. However, unintended exposures to antiandrogens often have adverse effects on the development and function of reproductive organs. This review discusses the impacts of antiandrogens on the female reproductive systems, focusing on environmental endocrine disruptors.

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KW - Endocrine disruptor

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PB - Elsevier

ER -

Female antiandrogens

Abstract

Keywords

ASJC Scopus subject areas

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