Feline oral squamous cell carcinoma: An overview

Jennifer J. Marretta, Laura D. Garrett, Sandra Manfra Marretta

Research output: Contribution to journalArticle


Oral squamous cell carcinoma is a common malignancy in cats that responds poorly to treatment. The ideal approach for management is early diagnosis by using oral examination, radiographic evaluation including advanced imaging techniques, biopsy, and radical surgical excision. Recurrence despite aggressive surgical resection is common, thus multimodality therapy appears to be indicated. Cats that have been treated with mandibulectomy and curative-intent radiation postoperatively have had the longest survival times. Mandibulectomy has a high associated morbidity, but the overall quality of life of the patients was thought to be good by most owners. Current research focuses on delineating the biologic pathways involved in malignant transformation and progression with the hope of improving therapeutic options for cats.

Original languageEnglish (US)
Pages (from-to)392-406
Number of pages15
JournalVeterinary Medicine
Issue number6
StatePublished - Jun 1 2007

ASJC Scopus subject areas

  • Small Animals

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    Marretta, J. J., Garrett, L. D., & Marretta, S. M. (2007). Feline oral squamous cell carcinoma: An overview. Veterinary Medicine, 102(6), 392-406.