Fatty acid supplementation and skin disease.

K. L. Campbell

Research output: Contribution to journalReview articlepeer-review


The importance of dietary fatty acids to the health of the skin was recognized more than 60 years ago. Fatty acids are important in providing membrane fluidity and maintaining the cutaneous water permeability barrier. Fatty acids function as precursors of eicosanoids. Eicosanoids, which include prostaglandins and leukotrienes, influence cellular interactions, cellular proliferation, and inflammation. Certain diseases, such as atopy and hypothyroidism, are characterized by abnormalities in fatty acid metabolism. Dietary manipulations may be useful in the treatment of diseases mediated by eicosanoids.

Original languageEnglish (US)
Pages (from-to)1475-1486
Number of pages12
JournalThe Veterinary clinics of North America. Small animal practice
Issue number6
StatePublished - Nov 1990

ASJC Scopus subject areas

  • Small Animals


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