@inproceedings{60cde5be1aeb48d6874dc4f7ad3b5c28,
title = "Fast High-Resolution Ultrasound Microvessel Imaging with Null Subtraction Imaging-based Beamforming",
abstract = "Recently, microvessel imaging at super resolution using contrast agents has been successfully demonstrated. However, the computational costs associated with the processing is extremely high. To overcome some of the computational issues, new techniques for generating high-resolution microvessel images with contrast MBs are warranted. One computationally inexpensive technique to realize high-resolution microvessel imaging is to use null subtraction imaging (NSI) [1]. NSI uses nulls in the beam pattern to produce images at much higher apparent lateral resolution and is especially suited for sharpening ultrasound images of specular scatters like MBs. In this study we acquired 1000 frames of ultrasonic data of chicken embryo with microbubble as contrast agent inside and utilized NSI to attain image with improved spatial resolution compared with traditional delay and sum image.",
keywords = "DAS, Microbubble, NSI, Super Resolution",
author = "Zhengchang Kou and Matt Lowerison and Pengfei Song and Oelze, {Michael L.}",
note = "I. INTRODUCTION Ultrasound localized microscopy (ULM) [2], [3], [4] and methods for improving ULM [5] have been proposed, which demonstrated its ability to achieve subwavelength resolution. By deconvolving the point spread function (PSF) formed by microbubbles, ULM could determine the center of the PSF, which is the position of microbubble to within micrometers of spatial resolution. In this way individual microbubbles could be isolated and tracked according from the ultrasound signal. However, this process is highly computational and expensive in terms of localizing each microbubbles. Recently, Null subtraction imaging (NSI) has been proved to be a computationally inexpensive method to improve the apparent lateral resolution in B-mode imaging by performing delay and sum (DAS) beamforming with three different apodization and subtracting the nulls in beam pattern to narrow the receive beamwidth. The computation cost is only three times of traditional DAS beamforming. In this study, we used NSI to replace DAS beamforming in power Doppler of ultrafast microvessel imaging with contrast microbubbles (MBs). We shows improved spatial resolution with the NSI technique This work was supported by grants from the NIH (R21EB024133) and NIH(R00CA214523).; 2020 IEEE International Ultrasonics Symposium, IUS 2020 ; Conference date: 07-09-2020 Through 11-09-2020",
year = "2020",
month = sep,
day = "7",
doi = "10.1109/IUS46767.2020.9251773",
language = "English (US)",
series = "IEEE International Ultrasonics Symposium, IUS",
publisher = "IEEE Computer Society",
booktitle = "IUS 2020 - International Ultrasonics Symposium, Proceedings",
}