TY - JOUR
T1 - Expression of lectin binding in cutaneous papillomas of animals
AU - Whiteley, H. E.
AU - Sundberg, J. P.
N1 - Funding Information:
This project was partially funded by the American Cancer Society, Illinois Division Inc., Grant No. 85-24 UPS) and NIH Grant EY06055 (HEW). We wish to thank D. Weise, M. Laasch, R. Vernon and D. Fritts for excellent technical assistance, and the Word Processing Centre for preparing the manuscript.
PY - 1988/7
Y1 - 1988/7
N2 - A group of spontaneously occurring animal papillomas which were negative or positive for papillomavirus group-specific antigen were examined with a battery of biotinylated lectins including Con A, WGA, succinylated-WGA, PNA and UEA-I. Canine papillomas, equine papillomas, white-tailed deer fibromas, mule deer fibromas, and bovine fibropapillomas were examined. Each lectin had a specific staining pattern. No obvious differences in staining patterns between normal skin, viral antigen-positive and -negative neoplasms were identified. This may be due to the well-differentiated and organized nature of these tumours.
AB - A group of spontaneously occurring animal papillomas which were negative or positive for papillomavirus group-specific antigen were examined with a battery of biotinylated lectins including Con A, WGA, succinylated-WGA, PNA and UEA-I. Canine papillomas, equine papillomas, white-tailed deer fibromas, mule deer fibromas, and bovine fibropapillomas were examined. Each lectin had a specific staining pattern. No obvious differences in staining patterns between normal skin, viral antigen-positive and -negative neoplasms were identified. This may be due to the well-differentiated and organized nature of these tumours.
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U2 - 10.1016/0021-9975(88)90107-7
DO - 10.1016/0021-9975(88)90107-7
M3 - Article
C2 - 2850306
AN - SCOPUS:0023898754
SN - 0021-9975
VL - 99
SP - 83
EP - 92
JO - Journal of Comparative Pathology
JF - Journal of Comparative Pathology
IS - 1
ER -