@article{f7c02e7a49a64cbb911b4874e3d11714,
title = "Exploring the possibilities for radical pair effects in cryptochrome",
abstract = "The ability of some animals to sense magnetic fields has long captured the human imagination. In our recent paper, we explored how radical pair effects in the protein cryptochrome may underlie the magnetic orientation sense of migratory birds. Here we explain our model and discuss its relationship to experimental results on plant cryptochromes, as well as discuss the next steps in refining our model, and explore alternate but related possibilities for modeling and understanding cryptochrome as a magnetic sensor.",
keywords = "Arabidopsis thaliana, Avian magnetoreception, Avian orientation, Cryptochrome, Magnetic field effect, Magnetic sensor, Radical pair machanism",
author = "Solov'yov, {Ilia A.} and Chandler, {Danielle E.} and Klaus Schulten",
note = "Funding Information: be devoid of hyperfine interactions. Such a radical pair, where one Acknowledgements radical has no hyperfine coupling, would be consistent with studies This work is supported by grants from the NIH P41-RR05969 on the effects of weak radio-frequency oscillating magnetic fields on and NSF MCB-0744057. The authors gladly acknowledge super-migratory bird orientation. Thorsten Ritz and co-workers found that computer time provided by Pittsburgh Supercomputing Center appropriate orientation behavior depended not only on the strength and the National Center for Supercomputing Applications via and angle of the oscillating field, but also that the minimum field LargeResourcesAllocationCommitteegrantMCA93S028andthe strength necessary to disrupt orientation depended on the frequency Turing Xserve Cluster. of the oscillating field in a resonance-like behavior that would be References predicted by just such a radical pair7-9 (personal communication 1. Fleissner G, Holtkamp-R{\"o}tzler E, Hanzlik M, Winklhofer M, Fleissner G, Petersen N, Bioscience. with T. Ritz). pigeons. J Comp Neurol 2003; 458:350-60.Wiltschko W. Ultrastructural analysis of a putative magnetoreceptor in the beak of homing",
year = "2008",
month = sep,
doi = "10.4161/psb.3.9.5809",
language = "English (US)",
volume = "3",
pages = "676--677",
journal = "Plant Signaling and Behavior",
issn = "1559-2316",
publisher = "Landes Bioscience",
number = "9",
}