Tracheal intubation of viable Pseudomonas aeruginosa into lungs of mice had no lethal effect on the animals. However, the treatment of animals with methotrexate, vincristine sulfate, or cytosine arabinoside simultaneously with the bacterial challenge into the lungs resulted in LD50 values of 4.1 x 107 CFU, 4.8 x 107 CFU, and 1.9 x 108 CFU, respectively.
|Title of host publication||IRCS Medical Science: Biochemistry|
|State||Published - Dec 1 1976|
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