Expanding the synthetic biology toolbox: Engineering orthogonal regulators of gene expression

Research output: Contribution to journalReview article

Abstract

Despite substantial progress in synthetic biology, we still lack the ability to engineer anything as complex as Nature has. One of the many reasons is that we lack the requisite tools for independently controlling the expression of multiple genes in parallel. While our toolbox is still spare, the situation is rapidly changing. This opinion discusses some recent approaches and open challenges in designing orthogonal regulators of gene expression in bacteria.

Original languageEnglish (US)
Pages (from-to)689-694
Number of pages6
JournalCurrent Opinion in Biotechnology
Volume23
Issue number5
DOIs
StatePublished - Oct 1 2012

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Synthetic Biology
Regulator Genes
Gene expression
Bacteria
Genes
Gene Expression
Engineers

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

Cite this

Expanding the synthetic biology toolbox : Engineering orthogonal regulators of gene expression. / Rao, Christopher V.

In: Current Opinion in Biotechnology, Vol. 23, No. 5, 01.10.2012, p. 689-694.

Research output: Contribution to journalReview article

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