Exercise Rehabilitation for People With End-Stage Kidney Disease: Who Will Fill the Gaps?

Stephanie Thompson, Michael K. Stickland, Kenneth Wilund, Gabor T. Gyenes, Clara Bohm

Research output: Contribution to journalReview articlepeer-review


Exercise rehabilitation is a well established therapy for reducing morbidity and mortality and improving quality of life and function across chronic conditions. People with dialysis-dependent kidney failure have a high burden of comorbidity and symptoms, commonly characterised as fatigue, dyspnoea, and the inability to complete daily activities. Despite more than 30 years of exercise research in people with kidney disease and its established benefit in other chronic diseases, exercise programs are rare in kidney care and are not incorporated into routine management at any stage. In this review, we describe the mechanisms contributing to exercise intolerance in those with end-stage kidney disease and outline the role of exercise rehabilitation in addressing the major challenges to kidney care: cardiovascular disease, symptom burden, and physical frailty. We also draw on existing models of exercise rehabilitation from other chronic conditions to inform the way forward and challenge the status quo of exercise rehabilitation in both practice and research.

Original languageEnglish (US)
Pages (from-to)S335-S345
JournalCanadian Journal of Cardiology
Issue number11
StatePublished - Nov 2023

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Exercise Rehabilitation for People With End-Stage Kidney Disease: Who Will Fill the Gaps?'. Together they form a unique fingerprint.

Cite this