Exercise, Inflammation, and Innate Immunity

Jeffrey A. Woods, Victoria J. Vieira, K. Todd Keylock

Research output: Contribution to journalReview article


Exercise has beneficial effects on chronic disease, and the drive to understand the mechanisms of these benefits is strong. This article presents several compelling potential mechanisms for the anti-inflammatory effect of exercise, including reduced percentage of body fat and macrophage accumulation in adipose tissue, muscle-released interleukin-6 inhibition of tumor necrosis factor-a, and the cholinergic anti-inflammatory pathway.

Original languageEnglish (US)
Pages (from-to)381-393
Number of pages13
JournalImmunology and Allergy Clinics of North America
Issue number2
StatePublished - May 1 2009


  • Exercise
  • Innate immunity
  • Macrophages

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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