Exercise, inflammation and aging

Jeffrey A. Woods, Kenneth R. Wilund, Stephen A. Martin, Brandon M. Kistler

Research output: Contribution to journalReview article

Abstract

Aging results in chronic low grade inflammation that is associated with increased risk for disease, poor physical functioning and mortality. Strategies that reduce age-related inflammation may improve the quality of life in older adults. Regular exercise is recommended for older people for a variety of reasons including increasing muscle mass and reducing risk for chronic diseases of the heart and metabolic systems. Only recently has exercise been examined in the context of inflammation. This review will highlight key randomized clinical trial evidence regarding the influence of exercise training on inflammatory biomarkers in the elderly. Potential mechanisms will be presented that might explain why exercise may exert an anti-inflammatory effect.

Original languageEnglish (US)
Pages (from-to)130-140
Number of pages11
JournalAging and Disease
Volume3
Issue number1
StatePublished - 2012

Keywords

  • Adipose
  • Aging
  • Elderly
  • Exercise
  • Inflammation

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Cell Biology
  • Clinical Neurology
  • Pathology and Forensic Medicine

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  • Cite this

    Woods, J. A., Wilund, K. R., Martin, S. A., & Kistler, B. M. (2012). Exercise, inflammation and aging. Aging and Disease, 3(1), 130-140.