Exercise and the Regulation of Inflammatory Responses

Jacob Allen, Yi Sun, Jeffrey A. Woods

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Exercise initiates a cascade of inflammatory events, which ultimately lead to long-term effects on human health. During and after acute exercise in skeletal muscle, interactions between immune cells, cytokines, and other intracellular components, create an inflammatory milieu responsible for the recovery and adaption from an exercise bout. In the systemic circulation, cytokines released from muscle (myokines) mediate metabolic and inflammatory processes. Moderate exercise training results in improvements in systemic inflammation, evident by reductions in acute phase proteins. The anti-inflammatory effects of regular exercise include actions dependent and independent of changes in adipose tissue mass. Future research should encompass approaches, which attempt to integrate other, less-recognized physiological processes with acute and long-term inflammatory changes. This will include investigation into metabolic, endocrine, and immune components of various tissues and organs.

Original languageEnglish (US)
Title of host publicationMolecular and Cellular Regulation of Adaptation to Exercise, 2015
EditorsClaude Bouchard
PublisherElsevier B.V.
Pages337-354
Number of pages18
ISBN (Print)9780128039915
DOIs
StatePublished - Jan 1 2015

Publication series

NameProgress in Molecular Biology and Translational Science
Volume135
ISSN (Print)1877-1173
ISSN (Electronic)1878-0814

Fingerprint

Exercise
Physiological Phenomena
Cytokines
Acute-Phase Proteins
Adipose Tissue
Skeletal Muscle
Anti-Inflammatory Agents
Inflammation
Muscles
Health

Keywords

  • Cytokines
  • Inflammation
  • Leukocytes
  • Macrophage
  • Repair
  • Toll-like receptors

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology

Cite this

Allen, J., Sun, Y., & Woods, J. A. (2015). Exercise and the Regulation of Inflammatory Responses. In C. Bouchard (Ed.), Molecular and Cellular Regulation of Adaptation to Exercise, 2015 (pp. 337-354). (Progress in Molecular Biology and Translational Science; Vol. 135). Elsevier B.V.. https://doi.org/10.1016/bs.pmbts.2015.07.003

Exercise and the Regulation of Inflammatory Responses. / Allen, Jacob; Sun, Yi; Woods, Jeffrey A.

Molecular and Cellular Regulation of Adaptation to Exercise, 2015. ed. / Claude Bouchard. Elsevier B.V., 2015. p. 337-354 (Progress in Molecular Biology and Translational Science; Vol. 135).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Allen, J, Sun, Y & Woods, JA 2015, Exercise and the Regulation of Inflammatory Responses. in C Bouchard (ed.), Molecular and Cellular Regulation of Adaptation to Exercise, 2015. Progress in Molecular Biology and Translational Science, vol. 135, Elsevier B.V., pp. 337-354. https://doi.org/10.1016/bs.pmbts.2015.07.003
Allen J, Sun Y, Woods JA. Exercise and the Regulation of Inflammatory Responses. In Bouchard C, editor, Molecular and Cellular Regulation of Adaptation to Exercise, 2015. Elsevier B.V. 2015. p. 337-354. (Progress in Molecular Biology and Translational Science). https://doi.org/10.1016/bs.pmbts.2015.07.003
Allen, Jacob ; Sun, Yi ; Woods, Jeffrey A. / Exercise and the Regulation of Inflammatory Responses. Molecular and Cellular Regulation of Adaptation to Exercise, 2015. editor / Claude Bouchard. Elsevier B.V., 2015. pp. 337-354 (Progress in Molecular Biology and Translational Science).
@inproceedings{1c24ce6c0cb442aeac21c9002ae46242,
title = "Exercise and the Regulation of Inflammatory Responses",
abstract = "Exercise initiates a cascade of inflammatory events, which ultimately lead to long-term effects on human health. During and after acute exercise in skeletal muscle, interactions between immune cells, cytokines, and other intracellular components, create an inflammatory milieu responsible for the recovery and adaption from an exercise bout. In the systemic circulation, cytokines released from muscle (myokines) mediate metabolic and inflammatory processes. Moderate exercise training results in improvements in systemic inflammation, evident by reductions in acute phase proteins. The anti-inflammatory effects of regular exercise include actions dependent and independent of changes in adipose tissue mass. Future research should encompass approaches, which attempt to integrate other, less-recognized physiological processes with acute and long-term inflammatory changes. This will include investigation into metabolic, endocrine, and immune components of various tissues and organs.",
keywords = "Cytokines, Inflammation, Leukocytes, Macrophage, Repair, Toll-like receptors",
author = "Jacob Allen and Yi Sun and Woods, {Jeffrey A.}",
year = "2015",
month = "1",
day = "1",
doi = "10.1016/bs.pmbts.2015.07.003",
language = "English (US)",
isbn = "9780128039915",
series = "Progress in Molecular Biology and Translational Science",
publisher = "Elsevier B.V.",
pages = "337--354",
editor = "Claude Bouchard",
booktitle = "Molecular and Cellular Regulation of Adaptation to Exercise, 2015",

}

TY - GEN

T1 - Exercise and the Regulation of Inflammatory Responses

AU - Allen, Jacob

AU - Sun, Yi

AU - Woods, Jeffrey A.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Exercise initiates a cascade of inflammatory events, which ultimately lead to long-term effects on human health. During and after acute exercise in skeletal muscle, interactions between immune cells, cytokines, and other intracellular components, create an inflammatory milieu responsible for the recovery and adaption from an exercise bout. In the systemic circulation, cytokines released from muscle (myokines) mediate metabolic and inflammatory processes. Moderate exercise training results in improvements in systemic inflammation, evident by reductions in acute phase proteins. The anti-inflammatory effects of regular exercise include actions dependent and independent of changes in adipose tissue mass. Future research should encompass approaches, which attempt to integrate other, less-recognized physiological processes with acute and long-term inflammatory changes. This will include investigation into metabolic, endocrine, and immune components of various tissues and organs.

AB - Exercise initiates a cascade of inflammatory events, which ultimately lead to long-term effects on human health. During and after acute exercise in skeletal muscle, interactions between immune cells, cytokines, and other intracellular components, create an inflammatory milieu responsible for the recovery and adaption from an exercise bout. In the systemic circulation, cytokines released from muscle (myokines) mediate metabolic and inflammatory processes. Moderate exercise training results in improvements in systemic inflammation, evident by reductions in acute phase proteins. The anti-inflammatory effects of regular exercise include actions dependent and independent of changes in adipose tissue mass. Future research should encompass approaches, which attempt to integrate other, less-recognized physiological processes with acute and long-term inflammatory changes. This will include investigation into metabolic, endocrine, and immune components of various tissues and organs.

KW - Cytokines

KW - Inflammation

KW - Leukocytes

KW - Macrophage

KW - Repair

KW - Toll-like receptors

UR - http://www.scopus.com/inward/record.url?scp=84938269017&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84938269017&partnerID=8YFLogxK

U2 - 10.1016/bs.pmbts.2015.07.003

DO - 10.1016/bs.pmbts.2015.07.003

M3 - Conference contribution

SN - 9780128039915

T3 - Progress in Molecular Biology and Translational Science

SP - 337

EP - 354

BT - Molecular and Cellular Regulation of Adaptation to Exercise, 2015

A2 - Bouchard, Claude

PB - Elsevier B.V.

ER -